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Aubrey de Grey on Progress and Timescales in Rejuvenation Research

Aubrey de Grey of the SENS Research Foundation maintains an active schedule of presentations, and the interview here is one of a series of recent discussions in which he talks about timelines, funding, and progress in recent years. We’re in the midst of a tipping point of sorts, as the SENS view of rejuvenation research gathers more attention and legitimacy in the eyes of the public and various sources of funding. Senolytic therapies to clear senescent cells are well into the first stages of clinical development, with new compelling data for cellular senescence to contribute to specific age-related diseases arriving every month now. Targeting senescent cells for destruction was one of the strategies that de Grey started to advocate all the way back in 2002, when the research community was much less welcoming of any discussion of the treatment of aging as a medical condition, and there was little to no funding for such approaches despite the extensive supporting evidence. It doesn’t hurt to be proven right when it comes to reinforcing an agenda.

Ministers announce £300 million fund to research old age as figures reveal ten million of us should live to 100

Ten million Britons alive today can expect to reach 100, new figures reveal
Ministers will inject more than £300 million into researching ageing population
Business Secretary Greg Clark will pledge to help make the country’s scientists world leaders in understanding ageing

Ten million Britons alive today can expect to reach 100, Government figures reveal.

Ministers will inject more than £300million into researching old age in order to support the ageing population. They say we need to ‘revolutionise’ the way people get older – ensuring they remain healthy and independent for longer.

What Silicon Valley is doing to make humans live longer

Peter Diamandis, co-founder of Celularity and Human Longevity, Inc., explains how Silicon Valley can make 100 the new 60. Click on the link below to see the video on www.uk.businessinsider.com or read the transcript.

http://uk.businessinsider.com/peter-diamandis-how-silicon-valley-can-make-100-new-60-2018-2

Following is a transcript of the video.

How Silicon Valley can make 100 the new 60. Peter Diamandis is an engineer, physician and entrepreneur. He is best known as founder of the XPRIZE Foundation. He is also co-founder of Celularity and Human Longevity, Inc. These companies work to extend the human life span.

Will Cutting Calories Make You Live Longer?

More than a decade ago, researchers at the Pennington Biomedical Research Center in Baton Rouge began recruiting young, healthy Louisianans to voluntarily go hungry for two years. In addition to cutting their daily calories by 25 percent, the dozens who enrolled also agreed to a weekly battery of tests; blood draws, bone scans, swallowing a pill that measures internal body temperature.

All that sticking and scanning and starving was in the name of the Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy, or Calerie—the largest human clinical trial ever to look at the effects of calorie restriction on aging. The National Institutes of Health-funded study also included sites at Washington University in St. Louis and Tufts in Boston. But only the Pennington participants had to also spend 24 sedentary hours inside a sealed room that recorded the contents of their every breath.

George Church Will Make Virus-Resistant Organisms, Transplant Pig Organs to Humans, and Reverse Aging.

You probably know the scientist George Church from the extravagant media headlines that have referred to his work in one way or another-about bringing back the wooly mammoth, using CRISPR to put an animated GIF inside living DNA, and curing (or reversing aging). By his own measure, the Harvard Medical School and MIT professor does say things that sound implausible.

“A lot of the things I said when I was young were ignored or ridiculed by people in my own lab,” Church said. “After a few work out, it flips to the other state where, even if I say ridiculous things, I’m not ridiculed. And even the most ridiculous things have a non-ridiculous version.”

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Following is a transcript of the video.

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